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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a30909d16e8452d39cb7e8276371170a44e55a0f6ca8c76868dd09ab4a35fef' 
  AND token = '6+t4qt+AwHqIW8kod0/SqmJSyWe3tV1zXblXdcyiBM4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}