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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '212289dc86c9066ff4e38d137a5245a88771f8a2710c71eac0552809851e54dd' 
  AND token = 'kacvaO53iVCRCQFsmcgG/+gtv9uDv0CBn4dMVug6rpk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}