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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4dcfd0d4588fcedb33f9d707975af9d6bd1e9cace1a756a40ce1e2f3f197002a' 
  AND token = '18m5MsQ/DoEzSYPMXMemdx1pOySpYk4F4WUFABdPLjw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}