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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a22d21f3ddc33fca419aba3ec70b603ee3710b80c265811bc4bf5d1743fddcc2' 
  AND token = '4YuxYSLEAgTp37Uw6vN6rX72839HXcLsC/AIwjl8jqo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}