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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '74d421c6626fa9117439e5c7f1f9b464e0b76bd12c1fd97a17936c8ad3451180' 
  AND token = 'rAhlaYktESxgNEGtJalXolfzxCUi9PdMh8q+HYM2HG4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}