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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1dbe370f902a01209a720092c08dfa5e606575cd42b1eaf0345c5b644d8dac0e' 
  AND token = '7Vrqht2pyLxUVM1DWP1joQj5NQyUi45VxbQ4f8NtBvI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}