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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '52225e0a8de2bc8c3921ba1b4dd23ad7c400acaa9354e31f05b83184180b54ce' 
  AND token = 'A0kkj+wCk/LVLGjSqTik11e0imYcezek8dawOimZqGI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}