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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c0f680b276c091d612a9265b743586cf4531af4e6af0612f319969c96ad486fb' 
  AND token = '2pTV9GeTw5nEmSdr/KXkL4JJHUDbH22RwumNcLetVi4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}