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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3d51be7a1766763846cb94d834dce8f08d4cce68117da76b16a033c1159ed4f9' 
  AND token = 'vU5TrdfibjXh+yiDMLaiLeiIOFo+OpuQLD7SLctvkfE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00118

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}