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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e50bcdb5b59a32e40c2993d9e51f61a9e35340408ac7c557600174cb0f5ad56c' 
  AND token = 'l2ZTMgFhwOYL7yhhlcrjrnDO8L6z4ARxYJ6gTqteccU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}