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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f9180b318eae3a9c8b147d198b36ff709f5fcd29564b88afaed84b5e241aa23e' 
  AND token = 'fq1mtb2JEUS26OMnqONuV9kN2s3u3pP8wLRXv+7Sho0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}