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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'db66a814c1735cc88518d8687602db6dc1b50240974a8f8c22da605e6d258f62' 
  AND token = '9pNY0ZZRo9YMZFZegZTJt5xo5MVlFS8WZtVYL+NrMEI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00030

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}