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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ca48566a20e870692bb148eca5565440c4455342a83b8e34644ecd54320a4398' 
  AND token = 'N5TXiKm0HGPyeHcb7pQEkXlpog6VUcLCdcuM9+rJ5UU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}