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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '87e1de03cad4db6d053bb242510f21cf618f18c813561546ccc36615736d5d7c' 
  AND token = 'jUG8ubYRZb1lpHXGbAkQUVp+6ip/JfVkvNyy72KMmRc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}