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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49d219417f159ad00c6404928d9c846f01d33e484f54c3f189af3b3c9bfcd9a3' 
  AND token = 'uPaCsxXHXyBkYNs5VhKG+4b0wk3jnzOHDIr8DjWqDIc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}