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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '656ed49264baeab44c00e9e405b6be3c5100ab9dbd127eee74269cefe17268ff' 
  AND token = 'GFRd7qmXdMP7xlHWLyDTyvod2F7Rh4CIFAb4oTVO9vs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}