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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8f72c09bf49a115efa473e77ebb291ceee17d68384a63004bc98b4c9508a3362' 
  AND token = '4M7Lu5oY0xNgLuZER/iPjgs/emvaMmAfNN1q6A9i2fM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}