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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54261ed1006e9b66bdf3a71a0f1b8e0470750c8404d3bf701fe9a8de53dfc623' 
  AND token = 'YDDFRO7C7uAlcArwvFhxY3lkP4NyZmfyy4UQyUVyZ9Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}