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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c23db557af1313425f5d4dc654c1b52d5ca4de6063cc06d95af0df502250a29' 
  AND token = 'YMqxk9XFNU0JNW9rT8VDckoxaffzsE3XBTv7OxbygEg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00038

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}