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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01f01a6c1f3a45d3e577d2c4587e76a962af592f3c2cc9be2e036872acc5d10b' 
  AND token = 'vksn2llsHKdGdlXiRDlke+E5+kbUoviFWzsj6n4usnw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}