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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e8adb875e35461312009ce0478deb8d779860e9934aec49b97a60e762e9a49a2' 
  AND token = '4pt9tZoeL9EHTbvd8t+bdB91P76XGs6tIRHe+u+H0uw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}