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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5e111eb236c702acf03faf4936a8027fd02f644de4364dcbe8ceb43de1c2b88d' 
  AND token = 'y3KLfhhoJpL0NFQOQS7Z0EQGBSAajMpX5Uo/zQdIrSw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00031

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}