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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4c66361cf931fb7efb41f7a39442a4da6e8f0188411c88dc1299227c29d54070' 
  AND token = 'fbk+JEbfDqpICDBwgZhXP7Fx+P1yj24pgLU4x9xFp0A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}