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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'd4cfac33627d12674ad66caa083071338fc637bdfaf1e324c4348a790d65b063' 
  AND token = 'iGwP8oPYtLdbZpTtYjwIhm6DTlht9R1+dUVU9uM4Dkg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}