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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '80b9c4cb6d61f41cf581320f6c717ee9cd3b12be456b1dc83fc4f10849e1c3a7' 
  AND token = 'FgP2d8pMBg8MAmM71y8BBIO/iWB0pSEME9ZbOIJ9QHA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}