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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1a76f29e0a4a902166ef135eb3d61ea242411a266d2d493e06fe6802480f7f43' 
  AND token = 'kuW7lQ3Wfmtenjfeda2zE0UqAWt0D44/hlq8mLTZW+Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}