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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f02274deafcbcf5ac62616b63a5c9acfcba9625baa2a1a289ee25adef209eb0' 
  AND token = '3E4Q/etoYsr1/WjXjxKlEb7vmu7Typ3UlGv0+tDP3vY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}