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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '25b9b001eb8c7008e30f4909c16dcc4d9de2a5830dc71a70288ffab03b3d8fd6' 
  AND token = 'qnBGQQdtEjgzLawl3iqOEk6v6pZTtMxe9KoUrD4jhdE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}