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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1b693eb25d5cd1bd94f4242cc8e335a54bd75390c7f09f3f329f53eed6536e5f' 
  AND token = 'tHb6m+XJk9YTNQgJv7gODXqxvSY5T1WC1j+Evu6abRs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}