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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '29e3a0cfe57fb60822f5a815933541b4cc27bff5acc01c8f6b697a13f0d32d13' 
  AND token = 'bURCoACM/OLokFTxv7jLFMNHulUnDaifEn+6EivDUys=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}