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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '89620e23fcdec7b48fd756f7d42c146d8d49c092ed1a2079a6555a425b6278d1' 
  AND token = 'y48b7uk/gLDA+N0hLl1/7PxYW9zxu1ZBqdLCf4LQYuA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}