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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '448149e7b352ab473ad8babb42a96a867b6d9ca52e67fb494e6a015acfc6fcf6' 
  AND token = 'XOTGyvFkN58ioYluGznD8SdAA4uzu1gjJHtEJP/W8Yc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}