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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6fc01d6d2039c54ddd7c17bc6f3e875f86c78d9c36354a12d4e78e618d98f90e' 
  AND token = 'HnTtmlNiOvmTrkX81zzuwA+7/va80zBI5zzck0Y+3Xw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}