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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '64cda161d4d29a4cca49c7e911ed0cd2fdae86a16733aaeee026382db33b0409' 
  AND token = '/ooi/EYGgEsm8QKZUBasdkv4WC+iyUSPNwAcJVspvzE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00056

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}