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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1c72eaeddbca17927eba2e12cd5e3d7c500f7712f32eec7f1e7be00c8a1fbe02' 
  AND token = 'hYXzIvvJXJrl0igE3Bq/SY9zukjtoKDFhl3hvcppgHY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}