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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '43fffa5f5d2e3483abd62e57c8ce203ba1066c2a3309f72082003e57810fa0d9' 
  AND token = 'q6gm6V1/4UBUWG1g1Zy4vPlQkdPdsd4tOJ5mSOoHEfI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}