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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '16cc797a7f7bfc3a150fbb3c28f6dde42a055fc1b479ca9af243d2a2f702fe85' 
  AND token = 'eiTX90wfaP7xNfqdO+49sVdg5HVqIhqfMIQZtTO1XQY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}