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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '676e7d51e4c525d0be937d5bdbe01151ad6165382fff35a5e292b518b8b7d868' 
  AND token = '0RHC6bOGGqbc0A+SertmcuOR3bo4ujwyF51cUzLIfY0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}