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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2b13cc4cf6fb3c9cb0ea8a57b900345154fde126c70d48d6db844427eec98524' 
  AND token = 'rV0al5XbzPcak8KFI6zjo6pLiL0UmqviGXyvdizU9X4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}