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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a5e700294c7a1703e32ca6c046bc5d99fcfffafde41a3fdc7f75f360793f4441' 
  AND token = '51QCL/cVUrPjTkww+NxWskCyF3uUk+DXOqPFSv4RXes=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00028

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}