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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '24b0af947cf1dc59cea81b171612e38b159b09f1aa89453e2380633cbf85e871' 
  AND token = 's3m/gLvDx4KMAHzi8txB+aYaZmLM+1N7VeuXlOM60RQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}