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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0b2655cc218dd41b9cf86b89bb533ac13160fac3f3d7706ac5901a3ccc8dd9f3' 
  AND token = '5EejoGKRWzoXUwxXEQJtir7Z7KwHQFv5Kp8tDPmRmAI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00018

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}