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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d5a4513d118977815a7ea771fe7371cbd63fb9113b722442cf2401d826b2c54' 
  AND token = 'Wa00cnzp+V9CDlp5tp5QVFTJkcQnpl5yS+JtJDvhgJY=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00017

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}