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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5b83b2ec502f14c257c047746090644622dc9fcedd2283028e58def1f0034ca4' 
  AND token = 'LT7MttyzzuCKY22mudd6w3Gg/jhKFdy0RshU4fWRq0k=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00019

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}