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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'dbcc68b99a026bd1aed15c5d6849c33fb00065c28fbe30b455e0040c60d4f823' 
  AND token = '+WdBMMCOvCaQ+B4GTYTMycgIXyl7QoJHJ0mecugLwPw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}