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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae9b4c29bc1f9e96a73849bbccec285ad231ca3fd4c400c658f0dc2640231c49' 
  AND token = 'o+wMg8cYxUt+JZCUMM3nbfZwBA2X2U50xW4ah/mE/+A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}