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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '7a4e36e6d2de542a008aae570d7d5b0ab25d79658f56cca674978df9b8e9b7eb' 
  AND token = 'z9HJUBMij0fl25x9xYm5SMtlMhmy9XSp2JKHv7ugng4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}