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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4d4b48ae033dae84daa2b3843745a7187c729bba07c29b243c20434c29c65ac6' 
  AND token = 'y7b+nEfv8ygHoGAyWdE9oS5o9PoPb+X3CKSLRqo++og=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00022

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}