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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2f19f6a2f40b67a16c95b3a5a4330a67425a218b09e52454f0efc1db1c635a6d' 
  AND token = 'XKPZOlrudVYQMEhw9/D8xVj3or0Z1IkZe4DNdQxnQdg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00023

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}