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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f29323e83c222d7f7ce001a21d90fb62eb2ccc542fd1f9f7734feb11d23eee74' 
  AND token = 'X9uwbSsuSaI/1ggeoD3pfKJ01nVHEcWzY0j7ZxKZI5g=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00035

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}